Professor Michael Levitt FRS (born 9 May 1947 in Pretoria, South Africa) is a biophysicist and Professor of Structural biology, Stanford University, California, since 1987.[9][10] His research is in computational biology[11] and he is a member of the National Academy of Sciences.
Michael Levitt received the 2013 Nobel Prize in Chemistry, together with Martin Karplus and Arieh Warshel for "the development of multiscale models for complex chemical systems". [12]
Education
Levitt was educated at King's College London graduating with a Bachelor of Science degree in Physics in 1967.[1][13]He went on to work at Gonville and Caius College, Cambridge gaining a PhD in Computational Biology in 1972.[14]
Research
Levitt is one of the first researchers who conducted molecular dynamics simulations of DNA and proteins and developed first software for this purpose.[15][16][17][18] He is currently well known for developing approaches to predict macromolecular structures, having participated in many Critical Assessment of Techniques for Protein Structure Prediction (CASP) competitions.[19] He has mentored many successful scientists, including Mark Gerstein and Ram Samudrala.[20] Cyrus Chothia was one of his colleagues.
He received the 2013 Nobel Prize in Chemistry, together with Martin Karplus and Arieh Warshel for "for the development of multiscale models for complex chemical systems". [21]
Career
Royal Society Exchange Fellow, Weizmann Institute, Israel, 1967–68
Staff Scientist, MRC Laboratory of Molecular Biology, Cambridge, 1973–80
Professor of Chemical Physics, Weizmann Institute, 1980-87.
References
^ to: a b "‘LEVITT, Prof. Michael’, Who's Who 2013, A & C Black, an imprint of Bloomsbury Publishing plc, 2013; online edn, Oxford University Press".(subscription required)
^ Diamond, R.; Levitt, M. (1971). "A refinement of the structure of lysozyme". The Biochemical journal 125 (4): 92P. PMC 1178298. PMID 5144255. edit
^ "Past colleagues in the Levitt Lab".
^ "Present colleagues in the Levitt Lab".
^ Xia, Y.; Huang, E. S.; Levitt, M.; Samudrala, R. (2000). "Ab initio construction of protein tertiary structures using a hierarchical approach". Journal of Molecular Biology 300 (1): 171–185. doi:10.1006/jmbi.2000.3835. PMID 10864507. edit
^ Gerstein, M.; Levitt, M. (1997). "A structural census of the current population of protein sequences". Proceedings of the National Academy of Sciences of the United States of America 94 (22): 11911–11916. doi:10.1073/pnas.94.22.11911. PMC 23653. PMID 9342336. edit
^ Pethica, R. B.; Levitt, M.; Gough, J. (2012). "Evolutionarily consistent families in SCOP: Sequence, structure and function". BMC Structural Biology 12: 27. doi:10.1186/1472-6807-12-27. PMC 3495643. PMID 23078280. edit
^ http://www.embo.org/embo-members/find-a-member.html Find an EMBO member
^ http://csb.stanford.edu/ Levitt Lab website
^ http://csb.stanford.edu/levitt/ Lab Website Profile Page
^ Levitt, M. (2001). "The birth of computational structural biology". Nature Structural Biology 8 (5): 392–393. doi:10.1038/87545. PMID 11323711. edit
^ "The Nobel Prize in Chemistry 2013" (Press release) (in English). Royal Swedish Academy of Sciences. October 09, 2013. Retrieved October 09, 2013.
^ http://csb.stanford.edu/levitt/2_Page_CV.html Michael Levitt CV
^ Levitt, Michael (1972). Conformation analysis of proteins (PhD thesis). University of Cambridge.
^ Chothia, C.; Lesk, A. M.; Tramontano, A.; Levitt, M.; Smith-Gill, S. J.; Air, G.; Sheriff, S.; Padlan, E. A.; Davies, D.; Tulip, W. R.; Colman, P. M.; Spinelli, S.; Alzari, P. M.; Poljak, R. J. (1989). "Conformations of immunoglobulin hypervariable regions". Nature 342 (6252): 877–883. Bibcode:1989Natur.342..877C. doi:10.1038/342877a0. PMID 2687698. edit
^ Levitt, M.; Chothia, C. (1976). "Structural patterns in globular proteins". Nature 261 (5561): 552–558. Bibcode:1976Natur.261..552L. doi:10.1038/261552a0. PMID 934293. edit
^ Warshel, A.; Levitt, M. (1976). "Theoretical studies of enzymic reactions: Dielectric, electrostatic and steric stabilization of the carbonium ion in the reaction of lysozyme". Journal of Molecular Biology 103 (2): 227–249. doi:10.1016/0022-2836(76)90311-9. PMID 985660. edit
^ Levitt, M. (1976). "A simplified representation of protein conformations for rapid simulation of protein folding". Journal of Molecular Biology 104 (1): 59–107. doi:10.1016/0022-2836(76)90004-8. PMID 957439. edit
^ Chopra, G.; Kalisman, N.; Levitt, M. (2010). "Consistent refinement of submitted models at CASP using a knowledge-based potential". Proteins: Structure, Function, and Bioinformatics 78 (12): n/a–n/a. doi:10.1002/prot.22781. PMC 2911515. PMID 20589633. edit
^ List of publications from Microsoft Academic Search
^ http://www.nobelprize.org/nobel_prizes/chemistry/laureates/2013/press.pdf
List of chemists
